Mat Reeves, BVSc, PhD

Chronic diseases, such as stroke, heart disease, cancer, and chronic pulmonary diseases, are by far the leading causes of mortality, morbidity, and disability in the world today. Epidemiology has contributed greatly to the understanding of the causes of these diseases, and thereby to the concepts of disease prevention and control. Much of the current chronic disease burden could be prevented if populations followed a few basic, health promotion steps – such as avoiding tobacco, avoiding excess alcohol, exercising regularly, eating a well-balanced diet, and making use of proven clinical preventive services. However, data show that the vast majority of people are unable to follow these basic recommendations. Similarly, major gains in reducing the chronic disease burden could be achieved by better application of the scientific and clinical knowledge we already have (i.e., knowledge translation). This is especially true in the area of hospital-based medical care and in the application of quality improvement strategies to improve the quality of care and outcomes of patients with chronic disease.

Mat Reeves’ academic interests in chronic diseases stem from a desire to blend the quantitative aspects of epidemiology with the practical aspects of disease prevention and public health. Current research activities include:

• Stroke registries –the development of hospital-based stroke registries designed to monitor and improve the care of acute stroke patients. This includes work with the MASCOTS Study, the Michigan Coverdell Registry (MOSAIC), and Get-With-The-Guidelines-Stroke.
• Improving transitional care for stroke patients and caregivers who return home following hospitalization for stroke: The Michigan Stroke Transitions Trial (MISTT) - a PCORI funded comparative effectiveness trial
• Sex differences in stroke outcomes – includes determining the causes of differences between men and women in functional outcomes, recovery, QOL, and access to acute care treatments.
• Understanding the epidemiology of behavioural lifestyles and physical activity.
• Methodological issues associated with hospital profiling of cardiovascular outcomes.

 

SELECTED PUBLICATIONS (see CV for full listing)

Stroke Registries:

Reeves MJ, Arora S, Broderick JP, Frankel M, Heinrich JP, Hickenbottom S, Karp H, LaBresh KA, Malarcher A, Moomaw CJ, Schwamm L, Weiss P, for the Paul Coverdell Prototype Registries Writing Group. Acute Stroke Care in the US: Results from Four Pilot Prototypes of the Paul Coverdell National Acute Stroke Registry. Stroke 2005; 36:1232-1240.

Reeves MJ, Mullard AJ, Wehner S. Inter-rater reliability of data elements from a prototype of the Paul Coverdell National Acute Stroke Registry. BMC Neurology 2008; 8:1-9.

Reeves MJ, Nickles AV, Roberts S, Hurst R, Lyon-Callo S. Assessment of the completeness and accuracy of case ascertainment in the Michigan Stroke Registry. Circ Cardiovasc Qual Outcomes. 2014 Sep;7(5):757-63.

Reeves MJ, Fonarow GC, Smith EE, Pan W, Olson D, Hernandez AF, Peterson ED, Schwamm LH. Representativeness of the Get With the Guidelines-Stroke Registry: comparison of patient and hospital characteristics among Medicare beneficiaries hospitalized with ischemic stroke. Stroke. 2012 Jan;43(1):44-9.

Nickles AV, Roberts S, Shell E, Mitchell M, Hussain S, Lyon-Callo S, Reeves
MJ. Characteristics and Outcomes of Stroke Patients Transferred to Hospitals
Participating in the Michigan Coverdell Acute Stroke Registry. Circ Cardiovasc
Qual Outcomes. 2016 May;9(3):265-74.

Improving stroke transitions (the MISTT Study):

Reeves MJ, Hughes AK, Woodward AT, Freddolino PP, Coursaris CK, Swierenga SJ, Schwamm LH, Fritz MC. Improving transitions in acute stroke patients discharged to home: the Michigan stroke transitions trial (MISTT) protocol. BMC Neurol. 2017 Jun 17;17(1):115.

Hughes AK, Woodward AT, Fritz MC, Reeves MJ. Improving stroke transitions: Development and implementation of a social work case management intervention. Soc Work Health Care. 2018 Feb;57(2):95-108.

Sex differences in stroke outcomes:

Gargano J, Reeves MJ. Sex differences in Stroke Recovery and Stroke-Specific Quality of Life: Results from a Statewide Stroke Registry. Stroke 2007; 38:2541-48.

Reeves MJ, Bhatt A, Jajou P, Brown M, Lisabeth L. Sex differences in the use of IV rt-PA thrombolysis treatment for acute ischemic stroke: A meta-analysis. Stroke 2009; 40:1743-49.

Bushnell C, McCullough LD, Awad IA, Chireau MV, Fedder WN, Furie KL, HowardVJ, Lichtman JH, Lisabeth LD, Piña IL, Reeves MJ, Rexrode KM, Saposnik G, Singh V, Towfighi A, Vaccarino V, Walters MR. Guidelines for the prevention of stroke in women: a statement for healthcare professionals from the AHA/ASA. Stroke. 2014 May;45(5):1545-88.

Phan HT, Blizzard CL, Reeves MJ, Thrift AG, Cadilhac D, Sturm J, Heeley E,
Otahal P, Konstantinos V, Anderson C, Parmar P, Krishnamurthi R, Barker-Collo S, Feigin V, Bejot Y, Cabral NL, Carolei A, Sacco S, Chausson N, Olindo S, Rothwell P, Silva C, Correia M, Magalhães R, Appelros P, Kõrv J, Vibo R, Minelli C, Gall S. Sex Differences in Long-Term Mortality After Stroke in the INSTRUCT (INternational STRoke oUtComes sTudy): A Meta-Analysis of Individual Participant Data. Circ Cardiovasc Qual Outcomes. 2017 Feb;10(2).

Behavioural lifestyles and physical activity:

Reeves MJ, Rafferty AP. Healthy lifestyle characteristics in adults in the United States, 2000. Arch Intern Med 2005;165:854-57.

Troost JP, Rafferty AP, Luo Z, Reeves MJ. Temporal and Regional Trends in the Prevalence of Healthy Lifestyle Characteristics: United States, 1994-2007. Am J Public Health. 2012 Jul;102(7):1392-8.

Reeves MJ, Rafferty AP, Miller CE, Lyon-Callo SK. The Impact of Dog Walking on Leisure-Time Physical Activity: Results from a Population-based Survey of Michigan Adults. J Phys Act Health. 2011; Mar;8(3):436-44.

Methodological issues associated with hospital profiling:

Austin PC, Reeves MJ. In response. The relationship between the C-statistic of a risk-adjustment model and the accuracy of hospital report cards: a Monte Carlo Study Med Care. 2013 Jul;51(7):633-5.

Austin PC, Reeves MJ. Effect of provider volume on the accuracy of hospital
report cards: a Monte Carlo study. Circ Cardiovasc Qual Outcomes. 2014 Mar;7(2):299-305.

Katzan IL, Spertus J, Bettger JP, Bravata DM, Reeves MJ, Smith EE, Bushnell C, Higashida RT, Hinchey JA, Holloway RG, Howard G, King RB, Krumholz HM, Lutz BJ, Yeh RW. Risk adjustment of ischemic stroke outcomes for comparing hospital performance: a statement for healthcare professionals from the AHA/ASA. Stroke. 2014 Mar;45(3):918-44.

 

COURSES TAUGHT

• Graduate course in Cardiovascular Disease Epidemiology and Prevention (EPI -815)
• Evidence-based Medicine (4 week Intersession delivered to 1st year medical students)