Previous Research


Cerebral Palsy Outreach Network (CPON) is an internet resource for children with cerebral palsy (CP) and their families (see The mission of CPON is to help families connect to needed services, provide scientific information about CP, and develop research on the causes and management of CP. CPON also helps sponsor a collaborative CP research in Michigan biennial conference. Nigel Paneth, PI.

Effect of Organochlorides on Male Infertility

This study investigated the relationship between measure of human male reproductive health, specifically semen quality and reproductive hormone levels, organochlorine compound environmental contaminants and polymorphisms in genes involved in contaminant and sex steroid metabolism Julie Wirth, PI Retired

Great Lakes Fisheater Study

Federally funded project assessing cognitive functioning in aging members of the Michigan Department of Community Health’s Lake Michigan Anglers cohort.

Joseph Gardiner, PI

MASCOTS and MOSAIC Stroke Registries

The Michigan Acute Stroke Care Overview & Treatment Surveillance System (MASCOTS) was a pilot representative, statewide, hospital-based surveillance system of acute stroke care that collected data from over 2000 acute stroke cases treated in 16 Michigan hospitals during the 2002-2003 period. This pilot registry led to the development of MOSAIC – a statewide hospital based registry that is part of the National Paul Coverdell Acute Stroke Registry run by CDC. MOSAIC is also part of the American Heart Association’s Get-With-The Guidelines quality improvement registry which now includes almost 5 million observations. For further information contact Mat Reeves (PI).


OSSM was inherited from Dr. Wilfried Karmaus. Its goal was to examine the association between organochlorine exposure and mRNA expression of sex steroid metabolites in female offspring of the original fisheater's project. Janet Osuch, PI, Retired


OWL (Origins, Wellness, and Lifehistory in CP) was funded by NIH to study the etiology of cerebral palsy. Cases and controls were recruited at ages 2-15 through hospital and medical practices, researchers and physicians in three metropolitan areas - Ann Arbor, Lansing, and Grand Rapids. The study collected information on pregnancy and birth histories, services for children, and analyzed newborn blood spots routinely collected and stored for newborn screening in the State of Michigan, to learn about infection, inflammation, coagulation and thyroid disorders, and perinatal asphyxia as possible causes of CP. Site staff members are Principal Investigators Madeleine Lenski, MSPH and Nigel Paneth, MD, MPH and Research Assistant Deborah Weiland, MSN.


With this application, the directors and the faculty of a NIDA-supported T32 institutional research training program on drug dependence epidemiology seek to enhance the international research and research training capacities of the training program, NIH, NIDA and Fogarty International Center. This project will link faculty and students of the Bloomberg School of Public Health with the Universidad Peruana Cayetano Heredia in Lima, Peru. Jim Anthony, PI

Clusters of Drug Involvement in Chile (FIRCA)

This is a collaborative, epidemiological research project studying the earliest stages of youthful drug involvement, including coca paste and other cocaine use in Chile.
Jim Anthony, PI


Multi-level analysis of disparities in Preterm Delivery

The purposes of the HRSA contract is to expand the use of multi-level modeling as a tool for examining the influences of neighborhood context on the risk of delivering prematurely, to disseminate examples of the analysis and develop strategies for instructing state and local maternal and child health (MCH) professionals on the value of contextual level variables and multi-level modeling, and help them to identify avenues for training in multi-level statistical techniques. Claudia Holzman, PI

K-Award: Drug Dependence

Drug Dependence Epidemiology and Enviromics

To combine enviromics, genetics, and epidemiology in research on drug dependence syndromes. Jim Anthony, PI

Perinatal Epidemiology Training Program

Trains pre and postdoctoral students in perinatal epidemiology.
Nigel Paneth, PI.

Polish Women Health Study

This international study looks at the “Effect of Changes in Diet and Other Factors on Breast Cancer Risk of Women Immigrants from Poland to the United States.”
Dorothy Pathak, PI

Research Training in Drug Dependence Epidemiology

Dr. James C. (Jim) Anthony serves as the director of our NIH/NIDA supported T32 and D43 research training fellowship programs based in the Department of Epidemiology within Michigan State University’s College of Human Medicine. Click here for more information


Young Women Health History Study Breast cancer is the most common cancer in women younger than 50 years of age. Though we have some understanding of why some women develop breast cancer and others do not, we have a lot more to learn about breast cancer prevention. The goal of the Young Women’s Health History Study is to find ways to reduce the risk of breast cancer in young women. Dorothy Pathak